Dafsolimab (SPV-T3a) is a murine monoclonal antibody of the IgG2a subclass, targeting the CD3 antigen on T cells. This antibody functions by modulating and activating the CD3/T cell receptor complex, subsequently inducing T cell death. Dafsolimab is primarily utilized in research focused on understanding and treating graft-versus-host disease (GVHD), offering significant insights into T cell behaviors and immune responses in this condition.
Dafsolimab (SPV-T3a) is a murine monoclonal antibody of the IgG2a subclass, targeting the CD3 antigen on T cells. This antibody functions by modulating and activating the CD3/T cell receptor complex, subsequently inducing T cell death. Dafsolimab is primarily utilized in research focused on understanding and treating graft-versus-host disease (GVHD), offering significant insights into T cell behaviors and immune responses in this condition.
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