Danirixin
目录号: A20792
CXCR2 拮抗剂
Danirixin 是一种选择性且可逆的 CXCR2 拮抗剂，对 CXCL8 的 IC50 为 12.5 nM。
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生物活性
| Discription | Danirixin is a selective, and reversible CXCR2 antagonist, with IC50?of?12.5 nM for CXCL8. | ||
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| Targets |
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产品信息
| 目录号 | A20792 |
|---|---|
| 分子式 | C19H21ClFN3O4S |
| 分子量 | 441.9 |
| CAS号 | 954126-98-8 |
| SMILES | O=C(NC1=CC=C(Cl)C(S([C@H]2CCCNC2)(=O)=O)=C1O)NC3=C(C)C(F)=CC=C3 |
| 其他名称 | GSK1325756, GSK 1325756, GSK-1325756 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 87 mg/mL (196.88 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.63 mL | 113.15 mL | 226.3 mL |
| 0.5 mM | 4.53 mL | 22.63 mL | 45.26 mL |
| 1 mM | 2.26 mL | 11.31 mL | 22.63 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.53 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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