Dapagliflozin (BMS512148)

Name: Dapagliflozin (BMS512148)
SKU: A10285
Price: 245 CNY
Rating: 5 (6 reviews)

目录号: A10285

SGLT2 抑制剂

6 篇发表文献

达格列净抑制钠-葡萄糖转运蛋白2型（SGLT2），该蛋白负责肾脏至少90%的葡萄糖重吸收。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥350.00	现货
25mg	¥455.00	现货
50mg	¥595.00	现货
100mg	¥770.00	现货
200mg	¥1,015.00	现货
500mg	¥1,960.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Dapagliflozin (BMS512148)发表的6篇文献

Tingting Ding, .et al. , J Diabetes Complications, 2024, Dec 9;39(2):108930 PMID: 39673870

David Papadopoli, .et al. , Neoplasia, 2021, Apr;23(4):391-399 PMID: 33784591

Neil Tanday, .et al. , Biochem Pharmacol, 2020, Jul;177:114009 PMID: 32360307

Subramaniam M, .et al. , Am J Physiol Regul Integr Comp Physiol, 2019, Nov 20 PMID: 31746628

Marina Subramaniam, .et al. , Physiol Rep, 2019, May; 7(9): e14090 PMID: 31062524

Angelopoulou A, .et al. , AAPS PharmSciTech, 2018, Feb;19(2):621-633 PMID: 8924948

生物活性

Discription

Dapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10285
分子式	C21H25ClO6
分子量	408.9
CAS号	461432-26-8
SMILES	CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	75 mg/mL (183.43 mM)
	Water	Insoluble
	Ethanol	15 mg/mL (36.68 mM)
In vivo	5% DMSO+40%PEG300+5% tween80+50% H2O	3.8 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.46 mL	122.28 mL	244.56 mL
0.5 mM	4.89 mL	24.46 mL	48.91 mL
1 mM	2.45 mL	12.23 mL	24.46 mL
5 mM	0.49 mL	2.45 mL	4.89 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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