Dapivirine
目录号: A12587
HIV reverse transcriptase 抑制剂
Dapivirine 是一种强效的非核苷类逆转录酶抑制剂（NNRTI）
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生物活性
| Discription | Dapivirine is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) | |||||
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| Targets |
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| Cell Research |
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产品信息
| 目录号 | A12587 |
|---|---|
| 分子式 | C20H19N5 |
| 分子量 | 329.4 |
| CAS号 | 244767-67-7 |
| SMILES | CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C |
| 其他名称 | R 147681; TMC 120; TMC 120R147681; |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 29 mg/mL (88.03 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.36 mL | 151.79 mL | 303.58 mL |
| 0.5 mM | 6.07 mL | 30.36 mL | 60.72 mL |
| 1 mM | 3.04 mL | 15.18 mL | 30.36 mL |
| 5 mM | 0.61 mL | 3.04 mL | 6.07 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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