Darapladib
目录号: A14274
Lp-PLA2 抑制剂
Darapladib 是一种可逆的脂蛋白相关磷脂酶A2（Lp-PLA2）抑制剂。
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生物活性
| Discription | Darapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor . | ||
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| Targets |
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产品信息
| 目录号 | A14274 |
|---|---|
| 分子式 | C36H38F4N4O2S |
| 分子量 | 666.77 |
| CAS号 | 356057-34-6 |
| SMILES | CCN(CC)CCN(CC1=CC=C(C=C1)C2=CC=C(C=C2)C(F)(F)F)C(=O)CN3C4=C(CCC4)C(=O)N=C3SCC5=CC=C(C=C5)F |
| 其他名称 | SB-480848 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Warmed: 96 mg/mL (143.97 mM) | |
| Water | Insoluble | ||
| Ethanol | 96 mg/mL (143.97 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15 mL | 74.99 mL | 149.98 mL |
| 0.5 mM | 3 mL | 15 mL | 30 mL |
| 1 mM | 1.5 mL | 7.5 mL | 15 mL |
| 5 mM | 0.3 mL | 1.5 mL | 3 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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