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Darapladib

促销

Lp-PLA2 抑制剂

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产品目录号: A14274

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Darapladib 5mg A14274-5
¥ 1,000.00
Darapladib 10mg A14274-10
¥ 1,800.00
Darapladib 25mg A14274-25
¥ 4,000.00
Darapladib 10mM * 1mL in DMSO A14274-10mM-D
¥ 1,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Darapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor .

Darapladib

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Chemical Information

目录号 A14274
Mechanism of action Inhibitor
分子量 666.77
化学分子式 C36H38F4N4O2S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 356057-34-6
Synonyms SB-480848
SMILES code CCN(CC)CCN(CC1=CC=C(C=C1)C2=CC=C(C=C2)C(F)(F)F)C(=O)CN3C4=C(CCC4)C(=O)N=C3SCC5=CC=C(C=C5)F
化学名称 N-[2-(diethylamino)ethyl]-2-[[(4-fluorophenyl)methyl]thio]-4,5,6,7-tetrahydro-4-oxo-N-[[4'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]methyl]-1H-Cyclopentapyrimidine-1-acetamide

生物活性

Description
Darapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor .
Targets
Lp-PLA2
0.25 nM

溶解性

Solubility (25°C)* In vitro DMSO 100 mg/mL heating (149.97 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (149.97 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15 mL 74.99 mL 149.98mL
0.5 mM 3 mL 15 mL 30 mL
1 mM 1.5 mL 7.5 mL 15 mL
5 mM 0.3 mL 1.5 mL 3 mL

*The above data is based on the productmolecular weight 666.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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