Darunavir
目录号: A20829
HIV protease 抑制剂
Darunavir 是一种 HIV 蛋白酶抑制剂。
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生物活性
| Discription | Darunavir is an HIV protease inhibitor | |||||
|---|---|---|---|---|---|---|
| Cell Research |
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产品信息
| 目录号 | A20829 |
|---|---|
| 分子式 | C27H37N3O7S |
| 分子量 | 547.66 |
| CAS号 | 206361-99-1 |
| SMILES | O=C(O[C@@H]1[C@@]2([H])[C@@](OCC2)([H])OC1)N[C@@H](CC3=CC=CC=C3)[C@H](O)CN(S(=O)(C4=CC=C(N)C=C4)=O)CC(C)C |
| 其他名称 | TMC114, TMC 114, TMC-114 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 93 mg/mL (169.81 mM) | |
| Water | Insoluble | ||
| Ethanol | 10 mg/mL (18.25 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.26 mL | 91.3 mL | 182.6 mL |
| 0.5 mM | 3.65 mL | 18.26 mL | 36.52 mL |
| 1 mM | 1.83 mL | 9.13 mL | 18.26 mL |
| 5 mM | 0.37 mL | 1.83 mL | 3.65 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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