Datopotamab (CDP7657) is a humanized monoclonal antibody targeting trophoblast cell surface antigen 2 (TROP2). This antibody serves as a foundational component for the development of antibody-drug conjugates (ADCs), particularly when conjugated with the DNA topoisomerase I inhibitor, Deruxtecan. Datopotamab is primarily utilized in research focused on triple-negative breast cancer and non-small cell lung cancer, providing a valuable tool for investigating therapeutic avenues in these challenging oncological contexts.
Datopotamab (CDP7657) is a humanized monoclonal antibody targeting trophoblast cell surface antigen 2 (TROP2). This antibody serves as a foundational component for the development of antibody-drug conjugates (ADCs), particularly when conjugated with the DNA topoisomerase I inhibitor, Deruxtecan. Datopotamab is primarily utilized in research focused on triple-negative breast cancer and non-small cell lung cancer, providing a valuable tool for investigating therapeutic avenues in these challenging oncological contexts.
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