dBET1

Name: dBET1
SKU: A16858
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A16858

BRD4 protein degrader

dBET1 是一种基于 PROTAC 技术的强效 BRD4 蛋白降解剂，其 EC50 为 430 nM。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥455.00	现货
5mg	¥700.00	现货
10mg	¥1,155.00	现货
25mg	¥2,030.00	现货
50mg	¥3,290.00	现货
100mg	¥5,005.00	现货
500mg	¥10,395.00	现货
*10mM 1mL in DMSO**	¥1,155.00	现货
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Data Sheet

SDS

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生物活性

Discription

dBET1 is a potent BRD4 protein degrader based on PROTAC technology with an EC50 of 430 nM.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A16858
分子式	C38H37ClN8O7S
分子量	785.27
CAS号	1799711-21-9
SMILES	O=C(NCCCCNC(COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4
其他名称	dBET-1, dBET 1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	89 mg/mL (113.33 mM)
	Water	<1 mg/mL
	Ethanol	35 mg/mL (44.57 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.73 mL	63.67 mL	127.34 mL
0.5 mM	2.55 mL	12.73 mL	25.47 mL
1 mM	1.27 mL	6.37 mL	12.73 mL
5 mM	0.25 mL	1.27 mL	2.55 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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