dBET57
目录号: A19133
BRD4BD1degrader
dBET57 是一种基于 PROTAC 技术的 BRD4BD1 的强效和选择性降解剂。
Discription | dBET57 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology. | ||
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Targets |
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目录号 | A19133 |
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分子式 | C34H31ClN8O5S |
分子量 | 699.18 |
CAS号 | 1883863-52-2 |
SMILES | O=C(NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4 |
其他名称 | dBET 57, dBET-57 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 89 mg/mL (127.29 mM) | |
Water | Insoluble | ||
Ethanol | 11 mg/mL (15.73 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 14.3 mL | 71.51 mL | 143.02 mL |
0.5 mM | 2.86 mL | 14.3 mL | 28.6 mL |
1 mM | 1.43 mL | 7.15 mL | 14.3 mL |
5 mM | 0.29 mL | 1.43 mL | 2.86 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2