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DBM 1285 dihydrochloride

p38 MAPK 抑制剂

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产品目录号: A16058

库存状态:中国现货中国现货

产品名 目录号 价格 数量
DBM 1285 dihydrochloride 5mg A16058-5
¥ 1,400.00
DBM 1285 dihydrochloride 10mg A16058-10
¥ 2,400.00
DBM 1285 dihydrochloride 50mg A16058-50
¥ 9,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

DBM 1285 dihydrochloride is a p38 MAPK inhibitor. Supresses p38 phosphorylation and LPS-induced TNF-α production in macrophages and in vivo.

DBM 1285 dihydrochloride

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Chemical Information

目录号 A16058
Mechanism of action Inhibitor
分子量 468.42
化学分子式 C21H22FN5S.2HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. N/AN/A
Synonyms 0
SMILES code FC(C=C4)=CC=C4C1=C(C2=CC=NC(NC5CC5)=N2)SC(C3CCNCC3)=N1.Cl.Cl
化学名称 N-Cyclopropyl-4-[4-(4-fluorophenyl)-2-(4-piperidinyl)-5-thiazolyl]-2-pyrimidinamine dihydrochloride

生物活性

Description
DBM 1285 dihydrochloride is a p38 MAPK inhibitor. Supresses p38 phosphorylation and LPS-induced TNF-α production in macrophages and in vivo.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.35 mL 106.74 mL 213.48mL
0.5 mM 4.27 mL 21.35 mL 42.7 mL
1 mM 2.13 mL 10.67 mL 21.35 mL
5 mM 0.43 mL 2.13 mL 4.27 mL

*The above data is based on the productmolecular weight 468.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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