DBPR112
目录号: A18857
EGFR 抑制剂
DBPR112 是一种口服活性的呋喃嘧啶基表皮生长因子受体抑制剂,其对 EGFRWT 和 EGFRL858R/T790M 的 IC50 分别为 15 nM 和 48 nM。
Discription | DBPR112 is an orally active Furanopyrimidine-Based Epidermal Growth Factor Receptor inhibitor with IC50s of 15 nM and 48 nM for EGFRWT and EGFRL858R/T790M, respectively. | |||||
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Targets |
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Cell Research |
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目录号 | A18857 |
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分子式 | C32H31N5O3 |
分子量 | 533.62 |
CAS号 | 1226549-49-0 |
SMILES | O=C(NC1=CC=CC(C2=C(C3=CC=CC=C3)OC4=NC=NC(N[C@@H](C5=CC=CC=C5)CO)=C42)=C1)/C=C/CN(C)C |
其他名称 | DBPR 112, DBPR-112 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2