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DC1SMe

DC1SMe

Name: DC1SMe
SKU: A20181

目录号: A20181

DC1SMe Chemical Structure

CAS NO. 501666-85-9

DC1Sme, a DC1 derivative, exhibits IC50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer.

库存：现货

规格	价格	数量
5 mg	￥ 4,950.00
10 mg	￥ 8,530.00
50 mg	￥ 25,300.00
100 mg	￥ 50,600.00

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制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.61 mL	73.07 mL	146.15 mL
0.5 mM	2.92 mL	14.61 mL	29.23 mL
1 mM	1.46 mL	7.31 mL	14.61 mL
5 mM	0.29 mL	1.46 mL	2.92 mL

*The above data is based on the productmolecular weight 684.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20181
M. Wt	684.23
Formula	C35H30ClN5O4S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	501666-85-9
SMILES	O=C(C(N1)=CC2=C1C=CC(NC(CCSSC)=O)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(O)C7=CC=CC=C67)=O)=C4)C=C3