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DCC-2618

C-Kit/PDGFR 抑制剂

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产品目录号: A15062

库存状态:中国现货中国现货

产品名 目录号 价格 数量
DCC-2618 5mg A15062-5
¥ 2,000.00
DCC-2618 10mg A15062-10
¥ 3,000.00
DCC-2618 50mg A15062-50
¥ 7,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

DCC-2618 is a small molecule inhibitor of c-Kit and PDGFR with IC50s of 6 nM/30 nM/13 nM for c-Kit/PDGFRα/PDGFRβ respectively.

DCC-2618

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Chemical Information

目录号 A15062
Mechanism of action Inhibitor
分子量 489.47
化学分子式 C26H21F2N5O3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1225278-16-9
Synonyms DCC2618, DCC 2618
SMILES code CN1C=C(C=N1)C2=NC=CC(=C2)OC3=C(C=C(C(=C3)F)NC(=O)C4(CC4)C(=O)NC5=CC=CC=C5)F
化学名称 1-N'-[2,5-difluoro-4-[2-(1-methylpyrazol-4-yl)pyridin-4-yl]oxyphenyl]-1-N-phenylcyclopropane-1,1-dicarboxamide

生物活性

Description
DCC-2618 is a small molecule inhibitor of c-Kit and PDGFR with IC50s of 6 nM/30 nM/13 nM for c-Kit/PDGFRα/PDGFRβ respectively.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.43 mL 102.15 mL 204.3mL
0.5 mM 4.09 mL 20.43 mL 40.86 mL
1 mM 2.04 mL 10.22 mL 20.43 mL
5 mM 0.41 mL 2.04 mL 4.09 mL

*The above data is based on the productmolecular weight 489.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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