DDR1-IN-1
目录号: A13985
DDR1 receptor 抑制剂
DDR1-IN-1 是一种强效且选择性的 DDR1 受体酪氨酸激酶抑制剂,其 IC50/EC50 为 105 nM/87 nM,对 DDR2 的抑制效力低 4 倍(IC50= 413 nM)。
Discription | DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM, 4-fold less potent for DDR2 (IC50= 413 nM). | |||||
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Cell Research |
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目录号 | A13985 |
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分子式 | C30H31F3N4O3 |
分子量 | 552.59 |
CAS号 | 1449685-96-4 |
SMILES | CCN1CCN(CC1)CC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)OC4=CC5=C(C=C4)NC(=O)C5)C(F)(F)F |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 87 mg/mL (157.44 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 3 mg/mL (5.42 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.1 mL | 90.48 mL | 180.97 mL |
0.5 mM | 3.62 mL | 18.1 mL | 36.19 mL |
1 mM | 1.81 mL | 9.05 mL | 18.1 mL |
5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2