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Chemical Information
目录号 | A14415 |
---|---|
Mechanism of action | Inhibitor |
分子量 | 356.38 |
化学分子式 | C20H16N6O |
Solubility | DMSO |
纯度 | >98% |
储存方式 | at -20°C 2 years |
CAS No. | 1265229-25-1 |
Synonyms | Debio 1347, Debio1347, CH5183284, CH 5183284, CH-5183284, FF-284, FF284, FF 284 |
SMILES code | CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=CC=CC=C5N4)N |
化学名称 | (5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone |
Description |
Debio-1347 is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity. | ||||||||||
Targets |
|
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 28.06 mL | 140.3 mL | 280.6mL |
0.5 mM | 5.61 mL | 28.06 mL | 56.12 mL |
1 mM | 2.81 mL | 14.03 mL | 28.06 mL |
5 mM | 0.56 mL | 2.81 mL | 5.61 mL |
*The above data is based on the productmolecular weight 356.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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