Debio-1347 (CH5183284)

目录号: A14415

FGFR1/2/3 抑制剂

Debio-1347 (CH5183284) Chemical Structure

CAS NO. 1265229-25-1

Debio-1347 is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity.

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 1,900.00
25 mg
¥ 3,300.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Debio-1347 is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity.
靶点信息
FGFR2 FGFR1 FGFR3 FGFR4
7.6 nM9.3 nM22 nM290 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.06 mL 140.3 mL 280.6 mL
0.5 mM 5.61 mL 28.06 mL 56.12 mL
1 mM 2.81 mL 14.03 mL 28.06 mL
5 mM 0.56 mL 2.81 mL 5.61 mL

*The above data is based on the productmolecular weight 356.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14415
MECHANISM OF ACTION Inhibitor
M. Wt 356.38
Formula C20H16N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1265229-25-1
Synonyms Debio 1347, Debio1347, CH5183284, CH 5183284, CH-5183284, FF-284, FF284, FF 284
SMILES CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=CC=CC=C5N4)N

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