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Debio-1347 (CH5183284)

FGFR1/2/3 抑制剂

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产品目录号： A14415

库存状态：中国现货中国现货

产品名 目录号 价格 数量
Debio-1347 5mg A14415-5
￥ 1,100.00
Debio-1347 10mg A14415-10
￥ 1,900.00
Debio-1347 25mg A14415-25
￥ 3,300.00

产品仅用于研究，不针对患者销售，望谅解.

产品简介

Debio-1347 is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity.

Debio-1347 (CH5183284)

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Chemical Information

目录号 A14415
Mechanism of action Inhibitor
分子量 356.38
化学分子式 C20H16N6O
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1265229-25-1
Synonyms Debio 1347, Debio1347, CH5183284, CH 5183284, CH-5183284, FF-284, FF284, FF 284
SMILES code CC1=NC2=C(N1)C=C(C=C2)N3C(=C(C=N3)C(=O)C4=CC5=CC=CC=C5N4)N
化学名称 (5-amino-1-(2-methyl-1H-benzo[d]imidazol-6-yl)-1H-pyrazol-4-yl)(1H-indol-2-yl)methanone

Biological Activity

Description
 Debio-1347 is an orally bioavailable inhibitor of the fibroblast growth factor receptor subtypes 1 (FGFR-1), 2 (FGFR-2) and 3 (FGFR-3), with potential antineoplastic activity.
Targets
FGFR2 FGFR1 FGFR3 FGFR4
7.6 nM9.3 nM22 nM290 nM

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