Decernotinib

目录号: A14012

JAK3 抑制剂

Decernotinib Chemical Structure

CAS NO. 944842-54-0

Decernotinib是Vertex开发的口服选择性Janus激酶3(JAK3)抑制剂。

库存: 现货

规格 价格 数量
2 mg
¥ 600.00
5 mg
¥ 900.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

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Decernotinib是Vertex开发的口服选择性Janus激酶3(JAK3)抑制剂。
靶点信息
JAK3 JAK1 JAK1 JAK2 TYK2
2.5 nM(Ki)11 nM11 nM(Ki)13 nM(Ki)13 nM(Ki)
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.49 mL 127.43 mL 254.85 mL
0.5 mM 5.1 mL 25.49 mL 50.97 mL
1 mM 2.55 mL 12.74 mL 25.49 mL
5 mM 0.51 mL 2.55 mL 5.1 mL

*The above data is based on the productmolecular weight 392.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A14012
MECHANISM OF ACTION Inhibitor
M. Wt 392.38
Formula C18H19F3N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 944842-54-0
Synonyms VX-509, VX509, VX 509, VRT-831509, VRT831509, VRT 831509
SMILES CC[C@](C)(C(=O)NCC(F)(F)F)NC1=NC(=NC=C1)C2=CNC3=C2C=CC=N3

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