Deforolimus (Ridaforolimus)

目录号: A10295

mTOR 抑制剂

Deforolimus (Ridaforolimus)

Deforolimus (Ridaforolimus) Chemical Structure

CAS NO. 572924-54-0

Deforolimus (Ridaforolimus)是mTOR蛋白的研究目标靶向小分子抑制剂。阻断mTOR通过干扰细胞生长,分裂,代谢和血管生成,在癌细胞中产生饥饿样的效应。

库存: 现货

规格 价格 数量
5 mg
¥ 550.00
10 mg
¥ 770.00
50 mg
¥ 2,960.00
100 mg
¥ 5,000.00
10mM * 1mL in DMSO
¥ 1,780.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Deforolimus (Ridaforolimus)是mTOR蛋白的研究目标靶向小分子抑制剂。阻断mTOR通过干扰细胞生长,分裂,代谢和血管生成,在癌细胞中产生饥饿样的效应。
靶点信息
mTOR (HT-1080 cells)
0.2 nM
In vitro (25°C) DMSO 196 mg/mL (197.93 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+40% PEG 300+5% Tween 80+50% H2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.1 mL 50.49 mL 100.99 mL
0.5 mM 2.02 mL 10.1 mL 20.2 mL
1 mM 1.01 mL 5.05 mL 10.1 mL
5 mM 0.2 mL 1.01 mL 2.02 mL

*The above data is based on the productmolecular weight 990.2. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10295
作用机制 Inhibitor (抑制剂)
M. Wt 990.2
Formula C53H84NO14P
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 572924-54-0
Synonyms AP23573, MK-8669, MK8669
SMILES C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OP(=O)(C)C)C)/C)O)OC)C)C)/C)OC

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