Depatuxizumab is a brain-penetrant, humanized monoclonal antibody specifically targeting the epidermal growth factor receptor (EGFR). This antibody demonstrates selective inhibition of both mutant EGFRvIII and wild-type EGFR, effectively impeding the growth of xenograft models that express these receptors. Depatuxizumab is primarily utilized in cancer research, offering significant utility in the study of tumor biology and therapeutic antibody development.
Depatuxizumab is a brain-penetrant, humanized monoclonal antibody specifically targeting the epidermal growth factor receptor (EGFR). This antibody demonstrates selective inhibition of both mutant EGFRvIII and wild-type EGFR, effectively impeding the growth of xenograft models that express these receptors. Depatuxizumab is primarily utilized in cancer research, offering significant utility in the study of tumor biology and therapeutic antibody development.
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