Depemokimab (GSK-3511294) is a long-acting, high-affinity human monoclonal antibody specifically targeting interleukin-5 (IL-5), a key cytokine involved in the proliferation, activation, and survival of eosinophils. Engineered for extended half-life and sustained biological activity, Depemokimab is designed to enable infrequent dosing while maintaining effective IL-5 pathway blockade.
This antibody is a valuable tool for preclinical research in eosinophilic asthma and other IL-5–mediated inflammatory diseases. Its pharmacokinetic and immunomodulatory properties make it suitable for evaluating long-term IL-5 inhibition in both in vitro and in vivo models.
Depemokimab (GSK-3511294) is a long-acting, high-affinity human monoclonal antibody specifically targeting interleukin-5 (IL-5), a key cytokine involved in the proliferation, activation, and survival of eosinophils. Engineered for extended half-life and sustained biological activity, Depemokimab is designed to enable infrequent dosing while maintaining effective IL-5 pathway blockade.
This antibody is a valuable tool for preclinical research in eosinophilic asthma and other IL-5–mediated inflammatory diseases. Its pharmacokinetic and immunomodulatory properties make it suitable for evaluating long-term IL-5 inhibition in both in vitro and in vivo models.
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