Dexrazoxane HCl
目录号: A10300
Dexrazoxane hydrochloride 是一种心脏保护剂。作为 EDTA 的衍生物,dexrazoxane 可以螯合铁,但其保护心脏的确切机制尚不清楚。这种药物用于保护心脏免受蒽环类药物(如多柔比星)的心脏毒性副作用。
Discription | Dexrazoxane hydrochloride is a cardioprotective agent. As a derivative of EDTA, dexrazoxane chelates iron, but the precise mechanism by which it protects the heart is not known. This agent is used to protect the heart against the cardiotoxic side effects of anthracyclines, such as doxorubicin. |
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目录号 | A10300 |
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分子式 | C11H17ClN4O4 |
分子量 | 304.7 |
CAS号 | 149003-01-0 |
SMILES | C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl |
其他名称 | Totect, ICRF-187, Zinecard, Cardioxane |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 55 mg/mL (180.48 mM) | |
Water | Warmed: 55 mg/mL (180.48 mM) | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 32.82 mL | 164.1 mL | 328.19 mL |
0.5 mM | 6.56 mL | 32.82 mL | 65.64 mL |
1 mM | 3.28 mL | 16.41 mL | 32.82 mL |
5 mM | 0.66 mL | 3.28 mL | 6.56 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2