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DG172 dihydrochloride

PPAR??/?? inverse 激动剂

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产品目录号: A16309


产品名 目录号 价格 数量
DG172 dihydrochloride 5mg A16309-5
¥ 500.00
DG172 dihydrochloride 10mg A16309-10
¥ 900.00
DG172 dihydrochloride 50mg A16309-50
¥ 3,600.00



DG-172 is an orally active potent PPARβ/δ inverse agonist (IC50 = 26.9 nM). DG-172 inhibits Angptl4 gene expression in mouse myoblasts (IC50 = 9.5 nM) in vitro.

DG172 dihydrochloride




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Chemical Information

目录号 A16309
Mechanism of action Antagonist
分子量 455.22
化学分子式 C20H22BrCl2N3
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1361504-77-9
Synonyms DG 172 dihydrochloride
SMILES code N#C/C(C1=CC=CC=C1Br)=C\C2=CC=C(N3CCN(C)CC3)C=C2.[H]Cl.[H]Cl
化学名称 (Z)-2-(2-bromophenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)acrylonitrile dihydrochloride


DG-172 is an orally active potent PPARβ/δ inverse agonist (IC50 = 26.9 nM). DG-172 inhibits Angptl4 gene expression in mouse myoblasts (IC50 = 9.5 nM) in vitro.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.97 mL 109.84 mL 219.67mL
0.5 mM 4.39 mL 21.97 mL 43.93 mL
1 mM 2.2 mL 10.98 mL 21.97 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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