Diclofenac sodium

目录号: A10304

COX 抑制剂

Diclofenac sodium

Diclofenac sodium Chemical Structure

CAS NO. 15307-79-6

Diclofenac Sodium是一种非选择性的COX抑制剂,完整细胞中的COX-1和-2的IC50分别为0.5μg/ml和0.5μg/ml,作用于绵羊COX-1和COX-2, IC50分别为60和220 nM,用作非甾体类抗炎药(NSAID)来减轻疼痛和减轻疼痛 肿胀发炎。

库存: 现货

规格 价格 数量
500 mg
¥ 450.00
10mM * 1mL in DMSO
¥ 680.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Diclofenac Sodium是一种非选择性的COX抑制剂,完整细胞中的COX-1和-2的IC50分别为0.5μg/ml和0.5μg/ml,作用于绵羊COX-1和COX-2, IC50分别为60和220 nM,用作非甾体类抗炎药(NSAID)来减轻疼痛和减轻疼痛 肿胀发炎。
靶点信息
COX-1 COX-2
60 nM200 nM
In vitro DMSO 54 mg/mL (169.74 mM)
Water 12 mg/mL (37.71 mM)
Ethanol 54 mg/mL (169.74 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.43 mL 157.17 mL 314.34 mL
0.5 mM 6.29 mL 31.43 mL 62.87 mL
1 mM 3.14 mL 15.72 mL 31.43 mL
5 mM 0.63 mL 3.14 mL 6.29 mL

*The above data is based on the productmolecular weight 318.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10304
作用机制 Inhibitor (抑制剂)
M. Wt 318.13
Formula C14H10Cl2NNaO2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 15307-79-6
SMILES C1=CC=C(C(=C1)CC(=O)[O-])NC2=C(C=CC=C2Cl)Cl.[Na+]

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