Diclofenac
目录号: A17814
COX 抑制剂
Diclofenac 是一种强效的非选择性抗炎药物,作为 COX 抑制剂,在 CHO 细胞中对人类 COX-1 和 COX-2 的 IC50 分别为 4 nM 和 1.3 nM,对绵羊 COX-1 和 COX-2 的 IC50 分别为 5.1 µM 和 0.84 µM。
Discription | Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively. | |||||
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Cell Research |
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目录号 | A17814 |
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分子式 | C14H11Cl2NO2 |
分子量 | 296.15 |
CAS号 | 15307-86-5 |
SMILES | O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 54 mg/mL (182.34 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 33.77 mL | 168.83 mL | 337.67 mL |
0.5 mM | 6.75 mL | 33.77 mL | 67.53 mL |
1 mM | 3.38 mL | 16.88 mL | 33.77 mL |
5 mM | 0.68 mL | 3.38 mL | 6.75 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2