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Diclofenac

目录号: A17814
COX 抑制剂
Diclofenac 是一种强效的非选择性抗炎药物,作为 COX 抑制剂,在 CHO 细胞中对人类 COX-1COX-2 的 IC50 分别为 4 nM 和 1.3 nM,对绵羊 COX-1COX-2 的 IC50 分别为 5.1 µM 和 0.84 µM。
Grouped product items
规格 价格 库存 数量
500mg
¥245.00
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5g
¥315.00
现货
10g
¥525.00
现货
10mM * 1mL in DMSO
¥280.00
现货
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生物活性
Discription Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 nM, 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1, 0.84 μM for ovine COX-1 and COX-2, respectively.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A17814
分子式 C14H11Cl2NO2
分子量 296.15
CAS号 15307-86-5
SMILES O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 54 mg/mL (182.34 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.77 mL 168.83 mL 337.67 mL
0.5 mM 6.75 mL 33.77 mL 67.53 mL
1 mM 3.38 mL 16.88 mL 33.77 mL
5 mM 0.68 mL 3.38 mL 6.75 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2

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