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Dihydroergotamine Mesylate

目录号: A17764
Serotonin receptors 激动剂
Dihydroergotamine Mesylate(又名DHE或Migranal)是一种麦角生物碱,用于治疗偏头痛。它与triptans具有类似的作用,作为serotonin受体的激动剂,并导致颅内血管的vasoconstriction,但也与中枢的dopamineadrenergic受体发生相互作用。
Grouped product items
规格 价格 库存 数量
5mg
¥175.00
现货
10mg
¥315.00
现货
50mg
¥385.00
现货
100mg
¥665.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Dihydroergotamine Mesylate, also known as DHE or Migranal, is an ergot alkaloid used to treat migraines. It has similar actions to the triptans, acting as an agonist to the serotonin receptors and causing vasoconstriction of the intracranial blood vessels, but also interacts centrally with dopamine and adrenergic receptors.
产品信息
目录号 A17764
分子式 C34H41N5O8S
分子量 679.78
CAS号 6190-39-2
SMILES O=C([C@@H](CN(C)[C@]1([H])C2)C[C@]1([H])C3=C4C2=CNC4=CC=C3)N[C@](C(N5[C@H]6CC7=CC=CC=C7)=O)(C)O[C@@]5(O)[C@]8([H])CCCN8C6=O.OS(=O)(C)=O
其他名称 Dihydroergotamine Mesylate; DHE; Migranal;
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 99 mg/mL (145.63 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.71 mL 73.55 mL 147.11 mL
0.5 mM 2.94 mL 14.71 mL 29.42 mL
1 mM 1.47 mL 7.36 mL 14.71 mL
5 mM 0.29 mL 1.47 mL 2.94 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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