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Dithranol

Dithranol

Name: Dithranol
SKU: A17404

目录号: A17404

Dithranol Chemical Structure

CAS NO. 1143-38-0

Anthralin, also known as Dithranol, is a hepsin activity inhibitor used for treatment of psoriasis Inhibition of hepsin activity suppresses the invasive growth of the tumor. Anthralin exerts a direct effect on keratinocytes and leukocytes. Anthralin significantly prolonged the prophase of mitotic keratinocytes in subtoxic doses and suppressed the expression of keratin 6 mRNA in the immediately suprabasal layer of psoriatic epidermis in vivo. Anthralin also inhibits the transformation of lymphocytes and the release of reactive oxygen species from activated leukocytes, in vitro.

库存：现货

规格	价格	数量
100 mg	￥ 500.00
500 mg	￥ 1,600.00

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产品详情

生物活性

溶解度 *

In vitro	DMSO	6 mg/mL (26.52 mM)
	Ethanol	<1 mg/mL
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	44.2 mL	221.01 mL	442.03 mL
0.5 mM	8.84 mL	44.2 mL	88.41 mL
1 mM	4.42 mL	22.1 mL	44.2 mL
5 mM	0.88 mL	4.42 mL	8.84 mL

*The above data is based on the productmolecular weight 226.231. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A17404
M. Wt	226.231
Formula	C14H10O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1143-38-0
Synonyms	Anthralin; Batridol; Dithranol; NSC 629313; NSC-629313; NSC629313
SMILES	O=C1C2=C(C=CC=C2O)CC3=CC=CC(O)=C13