DK419

Name: DK419
SKU: A19287
Price: 490 CNY
Rating: 5 (288 reviews)

目录号: A19287

Wnt/β-catenin signaling 抑制剂

DK419 是一种强效且可口服的 Wnt/β-catenin 信号通路抑制剂，其 IC50 为 0.19 μM。DK419 降低 Axin2、β-catenin、c-Myc、Cyclin D1 和 Survivin 的蛋白质水平，并诱导产生 pAMPK。

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规格	价格	库存
1mg	¥490.00	现货
5mg	¥1,155.00	现货
10mg	¥1,855.00	现货
25mg	¥3,115.00	现货
50mg	¥4,410.00	现货
100mg	¥5,950.00	现货
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SDS

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生物活性

Discription

DK419 is a potent and orally active Wnt/β-catenin signaling inhibitor, with an IC50 of 0.19 μM. DK419 reduces protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19287
分子式	C16H8ClF6N3O
分子量	407.7
CAS号	2102672-22-8
SMILES	O=C(C1=C2C(N=C(C(F)(F)F)N2)=CC(Cl)=C1)NC3=CC=C(C(F)(F)F)C=C3
其他名称	DK-419; DK 419
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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