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maytansinoid microtubular 抑制剂

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产品目录号: A15960


产品名 目录号 价格 数量
DM1-Sme 5mg A15960-5
¥ 3,200.00
DM1-Sme 10mg A15960-10
¥ 4,800.00
DM1-Sme 50mg A15960-50
¥ 14,000.00



DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group.





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Chemical Information

目录号 A15960
Mechanism of action Inhibitor
分子量 784.38
化学分子式 C36H50ClN3O10S2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 138148-68-2
Synonyms DM1-SSMe
SMILES code C[C@@H]1[C@@H]2C[C@](NC(O2)=O)(O)[C@H](OC)/C=C\C=C(C)\CC3=CC(N(C)C(C[C@@H](OC([C@@H](N(C(CCSSC)=O)C)C)=O)[C@@]4(C)C1O4)=O)=C(Cl)C(OC)=C3
化学名称 (14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl N-methyl-N-(3-(methyldisulfanyl)propanoyl)-L-alaninate


DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a mixed disulfide with thiomethane to cap its sulfhydryl group.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.75 mL 63.74 mL 127.49mL
0.5 mM 2.55 mL 12.75 mL 25.5 mL
1 mM 1.27 mL 6.37 mL 12.75 mL
5 mM 0.25 mL 1.27 mL 2.55 mL

*The above data is based on the productmolecular weight 784.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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