dMCL1-2

Name: dMCL1-2
SKU: A18378
Price: 2415 CNY
Rating: 5 (288 reviews)

目录号: A18378

MCL-1/PROTAC degrader

dMCL1-2 是一种基于 PROTAC 的强效且选择性的 MCL1（髓系细胞白血病1）降解剂，其与 MCL1 的结合 KD 为 30 nM。dMCL1-2 通过降解 MCL1 激活细胞凋亡机制。

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规格	价格	库存
5mg	¥2,415.00	现货
10mg	¥4,515.00	现货
50mg	¥13,965.00	现货
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Data Sheet

SDS

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生物活性

Discription	dMCL1-2 is a potent and selective degrader of myeloid cell leukemia 1 (MCL1) based on PROTAC, which binds to MCL1 with a KD of 30 nM. dMCL1-2 activats the cellular apoptosis machinery by degradation of MCL1.

产品信息

目录号	A18378
分子式	C61H66N10O12S
分子量	1163.3
CAS号	2351218-88-5
SMILES	O=S(N(CC1)CCN1C(C=C2)=CC=C2OCC3=C(C4=C(N(CCN5CCN(C(COC6=CC=CC(C(N7C8C(NC(CC8)=O)=O)=O)=C6C7=O)=O)CC5)C(C(O)=O)=C9CCCOC%10=C(C=CC=C%11)C%11=CC=C%10)C9=CC=C4)C(C)=NN3C)(N(C)C)=O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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