DMXAA (ASA404, Vadimezan)

目录号: A10324

Vascular Disrupting Agent (VDA)

DMXAA (ASA404, Vadimezan) Chemical Structure

CAS NO. 117570-53-3

DMXAA (ASA404) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
25 mg
¥ 2,600.00
50 mg
¥ 4,500.00
100 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,040.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

DMXAA (ASA404) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.
Targets
DT-diaphorase (Cell-free assay) DT-diaphorase (Cell-free assay)
20 μM(Ki)20 μM(Ki)
In vitro (25°C) DMSO 7 mg/mL (24.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.42 mL 177.12 mL 354.23 mL
0.5 mM 7.08 mL 35.42 mL 70.85 mL
1 mM 3.54 mL 17.71 mL 35.42 mL
5 mM 0.71 mL 3.54 mL 7.08 mL

*The above data is based on the productmolecular weight 282.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10324
MECHANISM OF ACTION
M. Wt 282.3
Formula C17H14O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 117570-53-3
Synonyms AS-1404, 5,6-MeXAA, NSC-640488, Vadimezan
SMILES CC1=C(C2=C(C=C1)C(=O)C3=C(O2)C(=CC=C3)CC(=O)O)C

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