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DMXAA (ASA404, Vadimezan)


Vascular Disrupting Agent (VDA)

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产品目录号: A10324


产品名 目录号 价格 数量
DMXAA (ASA404) 5mg A10324-5
¥ 800.00
DMXAA (ASA404) 25mg A10324-25
¥ 2,600.00
DMXAA (ASA404) 50mg A10324-50
¥ 4,500.00
DMXAA (ASA404) 100mg A10324-100
¥ 7,000.00
DMXAA (ASA404) 10mM * 1mL in DMSO A10324-10mM-D
¥ 1,040.00



DMXAA (ASA404) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.

DMXAA (ASA404, Vadimezan)




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 DMXAA (ASA404, Vadimezan) 发表的文献 (2)
  • Bowei Liu, .et al. A cell-based high throughput screening assay for the discovery of cGAS-STING pathway agonists, Antiviral Res, 2017, Nov; 147: 37每46 PMID: 28982551
  • Fang Guo, .et al. Activation of Stimulator of Interferon Genes in Hepatocytes Suppresses the Replication of Hepatitis B Virus, Antimicrob Agents Chemother, 2017, Oct; 61(10): e00771-17 PMID: 28717041

Chemical Information

目录号 A10324
Mechanism of action
分子量 282.3
化学分子式 C17H14O4
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 117570-53-3
Synonyms AS-1404, 5,6-MeXAA, NSC-640488, Vadimezan
SMILES code CC1=C(C2=C(C=C1)C(=O)C3=C(O2)C(=CC=C3)CC(=O)O)C
化学名称 (5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)-acetic acid


DMXAA (ASA404) is a tumor-vascular disrupting agent (tumor-VDA) that attacks the blood supply of a cancerous tumor to cause tumor regression.
DT-diaphorase (Cell-free assay) DT-diaphorase (Cell-free assay)
20 μM(Ki)20 μM(Ki)


Solubility (25°C) * In vitro DMSO 7 mg/mL (24.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.42 mL 177.12 mL 354.23mL
0.5 mM 7.08 mL 35.42 mL 70.85 mL
1 mM 3.54 mL 17.71 mL 35.42 mL
5 mM 0.71 mL 3.54 mL 7.08 mL

*The above data is based on the productmolecular weight 282.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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