Dolutegravir Sodium

目录号: A16162

HIV integrase inhibitor

Dolutegravir Sodium Chemical Structure

CAS NO. 1051375-19-9

Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.

库存: 现货

规格 价格 数量
5 mg
¥ 700.00
10 mg
¥ 950.00
50 mg
¥ 3,990.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.
Targets
HIV integrase
2.7 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.66 mL 113.29 mL 226.57 mL
0.5 mM 4.53 mL 22.66 mL 45.31 mL
1 mM 2.27 mL 11.33 mL 22.66 mL
5 mM 0.45 mL 2.27 mL 4.53 mL

*The above data is based on the productmolecular weight 441.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16162
MECHANISM OF ACTION Inhibitor
M. Wt 441.36
Formula C20H18F2N3NaO5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1051375-19-9
Synonyms DTG, GSK1349572
SMILES CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]

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