Dolutegravir Sodium

Name: Dolutegravir Sodium
SKU: A16162
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A16162

HIV integrase 抑制剂

多鲁特韦钠是一种HIV整合酶抑制剂（IC50= 2.7 nM），对拉替格韦耐药性突变体Y143R、Q148K、N155H和G140S/Q148H具有适度活性。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥245.00	现货
5mg	¥455.00	现货
10mg	¥630.00	现货
25mg	¥1,295.00	现货
50mg	¥1,960.00	现货
100mg	¥2,835.00	现货
500mg	¥6,545.00	现货
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Data Sheet

SDS

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生物活性

Discription

Dolutegravir sodium is a HIV integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A16162
分子式	C20H18F2N3NaO5
分子量	441.36
CAS号	1051375-19-9
SMILES	CC1CCOC2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)[O-].[Na+]
其他名称	DTG, GSK1349572
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	0.18 mg/mL (0.41 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.66 mL	113.29 mL	226.57 mL
0.5 mM	4.53 mL	22.66 mL	45.31 mL
1 mM	2.27 mL	11.33 mL	22.66 mL
5 mM	0.45 mL	2.27 mL	4.53 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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