Donepezil
目录号: A13079
AChE 抑制剂
Donepezil 是一种非竞争性乙酰胆碱酯酶抑制剂，能够轻松穿过血脑屏障并增加皮层乙酰胆碱的浓度。众所周知，Donepezil 是研究阿尔茨海默病的有用工具。
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生物活性
| Discription | Donepezil is a noncompetitive acetylcholineesterase inhibitor, which can readily cross the blood brain barrier and increase the concentration of cortical acetylcholine. It is known that Donepezil is a useful tool in the study of Alzheimer's disease. | |||||
|---|---|---|---|---|---|---|
| Cell Research |
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产品信息
| 目录号 | A13079 |
|---|---|
| 分子式 | C24H29NO3 |
| 分子量 | 379.5 |
| CAS号 | 120014-06-4 |
| SMILES | COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 68 mg/mL (179.18 mM) | |
| Ethanol | <1 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.35 mL | 131.75 mL | 263.5 mL |
| 0.5 mM | 5.27 mL | 26.35 mL | 52.7 mL |
| 1 mM | 2.64 mL | 13.18 mL | 26.35 mL |
| 5 mM | 0.53 mL | 2.64 mL | 5.27 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 120014-06-4 | 120014-06-4 供应商 | 120014-06-4 花费 | 120014-06-4 生产商 | 订购 120014-06-4 | 120014-06-4 代理商