|p38α (Cell-free assay)||p38α|
|0.1 nM(Kd)||38 nM|
|In vitro (25°C)||DMSO||106 mg/mL (200.88 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||106 mg/mL (200.88 mM)|
|In vivo||30% PEG400/0.5% Tween80/5% propylene glycol||30 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||18.95 mL||94.75 mL||189.5 mL|
|0.5 mM||3.79 mL||18.95 mL||37.9 mL|
|1 mM||1.9 mL||9.48 mL||18.95 mL|
|5 mM||0.38 mL||1.9 mL||3.79 mL|
*The above data is based on the productmolecular weight 527.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
|MECHANISM OF ACTION||Inhibitor|
|Storage||at -20°C 3 years Powder|
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