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DOTA-LM3

目录号: A23503
DOTA-LM3 是一种生长抑素受体(SSTR)拮抗剂。LM3 指的是 p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2,也是一种生长抑素拮抗剂。DOTA-LM3 常用同位素标记来追踪体内肿瘤,例如 177Lu-DOTA-LM3 和 68 Ga-DOTA-LM3。68 Ga-DOTA-LM3 显示出良好的生物分布、高肿瘤摄取率、良好的肿瘤保留性和较少的安全问题。177Lu-DOTA-LM3 可用于研究 DOTATOC 阴性肝转移,如胰腺NET和广泛的肿瘤血栓。
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规格 价格 库存 数量
1mg
¥630.00
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5mg
¥1,960.00
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10mg
¥2,975.00
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis.
产品信息
目录号 A23503
分子式 C69H93ClN16O19S2
分子量 1550.16
CAS号 1192362-32-5
Sequence DOTA-[p-Cl-Phe-cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr-NH2]
其他名称 SSTR antagonist
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