Dovitinib lactate

Name: Dovitinib lactate
SKU: A21851

目录号: A21851

FGFR3 inhibitor

Dovitinib lactate Chemical Structure

CAS NO. 692737-80-7

Dovitinib(CHIR-258; TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) with an IC50 of 5 nM.

库存：现货

规格	价格	数量
5 mg	￥ 540.00
10 mg	￥ 930.00
50 mg	￥ 2,760.00
100 mg	￥ 5,520.00

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生物活性

Dovitinib(CHIR-258; TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) with an IC50 of 5 nM.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.72 mL	103.62 mL	207.25 mL
0.5 mM	4.14 mL	20.72 mL	41.45 mL
1 mM	2.07 mL	10.36 mL	20.72 mL
5 mM	0.41 mL	2.07 mL	4.14 mL

*The above data is based on the productmolecular weight 482.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A21851
作用机制	Inhibitor (抑制剂)
M. Wt	482.51
Formula	C24H27FN6O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	692737-80-7
Synonyms	CHIR-258 lactate, CHIR258, CHIR 258; TKI-258 lactate, TKI258, TKI 258
SMILES	O=C(N1)C(C(NC2=C3)=NC2=CC=C3N4CCN(C)CC4)=C(N)C5=C1C=CC=C5F.O=C(O)C(C)O