Doxapram
目录号: A15961
Doxapram 抑制 TASK-1、TASK-3、TASK-1/TASK-3 杂合二聚体通道的功能，其 EC50 分别为 410 nM、37 μM、9 μM。Doxapram 是一种呼吸兴奋剂。通过静脉注射，doxapram 可以刺激潮气量和呼吸频率的增加。
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生物活性
| Discription | Doxapram inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively. Doxapram is a respiratory stimulant. Administered intravenously, doxapram stimulates an increase in tidal volume, and respiratory rate. |
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产品信息
| 目录号 | A15961 |
|---|---|
| 分子式 | C24H30N2O2 |
| 分子量 | 378.52 |
| CAS号 | 309-29-5 |
| SMILES | O=C1N(CC)CC(CCN2CCOCC2)C1(C3=CC=CC=C3)C4=CC=CC=C4 |
| 其他名称 | AHR-619, AHR 619, AHR619 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 68 mg/mL (179.65 mM) | |
| Water | Insoluble | ||
| Ethanol | 68 mg/mL (179.65 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.42 mL | 132.09 mL | 264.19 mL |
| 0.5 mM | 5.28 mL | 26.42 mL | 52.84 mL |
| 1 mM | 2.64 mL | 13.21 mL | 26.42 mL |
| 5 mM | 0.53 mL | 2.64 mL | 5.28 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 309-29-5 | 309-29-5 供应商 | 309-29-5 花费 | 309-29-5 生产商 | 订购 309-29-5 | 309-29-5 代理商