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Topoisomerase II 抑制剂

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产品目录号: A14403


产品名 目录号 价格 数量
Doxorubicin 50mg A14403-50
¥ 450.00
Doxorubicin 100mg A14403-100
¥ 750.00
Doxorubicin 500mg A14403-500
¥ 2,500.00



Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.





顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 Doxorubicin 发表的文献 (2)
  • Abdelrehim A, .et al. The use of tail-anchored protein chimeras to enhance liposomal cargo delivery, PLoS One, 2019, Feb 22;14(2):e0212701 PMID: 30794671
  • J Wei, .et al. Profiling the surface proteome identifies actionable biology for TSC1 mutant cells beyond mTORC1 signaling, bioRxiv, 2018, 2018

Chemical Information

目录号 A14403
Mechanism of action Inhibitor
分子量 543.52
化学分子式 C27H29NO11
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 23214-92-8
Synonyms Adriamycin, Hydroxydaunorubicin
SMILES code C[C@H]1[C@H]([C@H](C[C@@H](O1)O[C@H]2C[C@@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O
化学名称 (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione


Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 91.99 mL 183.99mL
0.5 mM 3.68 mL 18.4 mL 36.8 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL

*The above data is based on the productmolecular weight 543.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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