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DPPI 1c hydrochloride

DPP-4 抑制剂

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产品目录号: A15298

库存状态:中国现货中国现货

产品名 目录号 价格 数量
DPPI 1c hydrochloride 1mg A15298-1
¥ 950.00
DPPI 1c hydrochloride 10mg A15298-10
¥ 1,950.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

DPPI 1c hydrochloride is a dicyanopyrrolidine compound that acts as a slow-binding and active site-targeting inhibitor of CD26 (DPP 4), with an IC50 = 106 nM and little activity against DPP II, DPP III, DPP VIII, DPP IX, FAP, or APP even at concentrations as high as 30 μM.

DPPI 1c hydrochloride

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Chemical Information

目录号 A15298
Mechanism of action Inhibitor
分子量 312.8
化学分子式 C14H20N4O2.HCl
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 866396-34-1
Synonyms Dipeptidylpeptidase IV Inhibitor III
SMILES code C1CCC(C1)(CO)NCC(=O)N2C(CCC2C#N)C#N.Cl
化学名称 (2S,5R)-1-(2-((1-(hydroxymethyl)cyclopentyl)amino)acetyl)pyrrolidine-2,5-dicarbonitrile hydrochloride

生物活性

Description
DPPI 1c hydrochloride is a dicyanopyrrolidine compound that acts as a slow-binding and active site-targeting inhibitor of CD26 (DPP 4), with an IC50 = 106 nM and little activity against DPP II, DPP III, DPP VIII, DPP IX, FAP, or APP even at concentrations as high as 30 μM.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.97 mL 159.85 mL 319.69mL
0.5 mM 6.39 mL 31.97 mL 63.94 mL
1 mM 3.2 mL 15.98 mL 31.97 mL
5 mM 0.64 mL 3.2 mL 6.39 mL

*The above data is based on the productmolecular weight 312.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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