Durvalumab (MEDI4736) is a human monoclonal antibody targeting PD-L1. This antibody effectively inhibits the interaction of PD-L1 with its receptors PD-1 and CD80, demonstrating inhibitory concentrations (IC50) of 0.1 nM and 0.04 nM, respectively. Durvalumab's high specificity and potent binding affinity make it a valuable tool for research into checkpoint inhibition and immune response modulation.
Durvalumab (MEDI4736) is a human monoclonal antibody targeting PD-L1. This antibody effectively inhibits the interaction of PD-L1 with its receptors PD-1 and CD80, demonstrating inhibitory concentrations (IC50) of 0.1 nM and 0.04 nM, respectively. Durvalumab's high specificity and potent binding affinity make it a valuable tool for research into checkpoint inhibition and immune response modulation.
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