Dxd

目录号: A21517

DNA topoisomerase I inhibitor

Dxd

Dxd Chemical Structure

CAS NO. 1599440-33-1

Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).

库存: 现货

规格 价格 数量
1 mg
¥ 4,680.00
5 mg
¥ 14,040.00
10 mg
¥ 23,920.00
50 mg
¥ 71,760.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Dxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.26 mL 101.32 mL 202.64 mL
0.5 mM 4.05 mL 20.26 mL 40.53 mL
1 mM 2.03 mL 10.13 mL 20.26 mL
5 mM 0.41 mL 2.03 mL 4.05 mL

*The above data is based on the productmolecular weight 493.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21517
作用机制 Inhibitor (抑制剂)
M. Wt 493.48
Formula C26H24FN3O6
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1599440-33-1
Synonyms Exatecan derivative for ADC
SMILES O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[C@@H]5NC(CO)=O)C(C)=C(F)C=C6N=C4C3=C2)=O

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