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E 2012

gamma-secretase modulator

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产品目录号: A11393


产品名 目录号 价格 数量
E 2012 5mg A11393-5
¥ 2,800.00
E 2012 10mg A11393-10
¥ 5,000.00
E 2012 25mg A11393-25
¥ 8,500.00
E 2012 50mg A11393-50
¥ 15,000.00



E 2012 is γ-secretase inhibitor.

E 2012




顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 E 2012 发表的文献 (1)
  • Yesuvadian R, .et al. Potent 污-secretase inhibitors/modulators interact with amyloid-汕 fibrils but do not inhibit fibrillation: a high-resolution NMR study., Biochem Biophys Res Commun., 2014, May 16;447(4):590-5 PMID: 24747079

Chemical Information

目录号 A11393
Mechanism of action Modulator
分子量 419.49
化学分子式 C25H26FN3O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 870843-42-8
Synonyms E-2012,E2012
SMILES code CC1=CN(C=N1)C2=C(C=C(C=C2)/C=C/3\CCCN(C3=O)[C@@H](C)C4=CC=C(C=C4)F)OC
化学名称 (E)-1-[(1S)-1-(4-Fluorophenyl)ethyl]-3-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)benzylidene]piperidin-2-one


E 2012 is γ-secretase inhibitor.


Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.84 mL 119.19 mL 238.38mL
0.5 mM 4.77 mL 23.84 mL 47.68 mL
1 mM 2.38 mL 11.92 mL 23.84 mL
5 mM 0.48 mL 2.38 mL 4.77 mL

*The above data is based on the productmolecular weight 419.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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