微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
E-7050 (Golvatinib)是具有潜在抗肿瘤活性的c-Met(肝细胞生长因子受体)和VEGFR-2(血管内皮生长因子受体-2)酪氨酸激酶的口服生物可利用双重激酶抑制剂。
靶点信息
| c-Met | VEGFR2 | |||
| 14 nM | 16 nM |
| In vitro (25°C) | DMSO | 18 mg/mL (28.4 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.78 mL | 78.9 mL | 157.81 mL |
| 0.5 mM | 3.16 mL | 15.78 mL | 31.56 mL |
| 1 mM | 1.58 mL | 7.89 mL | 15.78 mL |
| 5 mM | 0.32 mL | 1.58 mL | 3.16 mL |
*The above data is based on the productmolecular weight 633.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11396 |
|---|---|
| M. Wt | 633.69 |
| Formula | C33H37F2N7O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 928037-13-2 |
| SMILES | CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Brivanib (BMS-540215)
Brivanib (BMS-540215)是一种VEGFR-2抑制剂，IC50为25 nM，Ki为26 nM。
BMS-690514
BMS-690514是一种有效的选择性表皮生长因子受体（EGFR），HER2和HER4抑制剂，以及VEGF受体激酶。
Imatinib (Gleevec)
Imatinib (Gleevec)是一种多靶点酪氨酸激酶抑制剂，抑制v-Abl、c-Kit和PDGFR的IC50分别为0.6，0.1和0.1 μM。
Raf265 derivative
Raf265 derivative是Raf265的衍生物，Raf265是一种口服，高度选择性的RAF和VEGFR激酶抑制剂，IC50为5至10μM。
Bibf1120 (Nintedanib)
Bibf1120 (Nintedanib)是一种新型的三联血管激酶抑制剂，可同时抑制三种生长因子受体：VEGFR，PDGF和FGFR。
Keywords:购买 E-7050 (Golvatinib) | E-7050 (Golvatinib) 供应商 | 订购 E-7050 (Golvatinib) | E-7050 (Golvatinib) 价格 | E-7050 (Golvatinib) 生产商 | 订单 E-7050 (Golvatinib) | E-7050 (Golvatinib) 代理商 | 购买 928037-13-2| 928037-13-2 供应商 | 订购 928037-13-2 | 928037-13-2 价格 | 928037-13-2 生产商 | 订单 928037-13-2 | 928037-13-2 代理商|buy E-7050 (Golvatinib) | E-7050 (Golvatinib) Supplier | purchase E-7050 (Golvatinib) | E-7050 (Golvatinib) cost | E-7050 (Golvatinib) manufacturer | order E-7050 (Golvatinib) | E-7050 (Golvatinib) distributor | buy 928037-13-2| 928037-13-2 Supplier | purchase 928037-13-2 | 928037-13-2 cost | 928037-13-2 manufacturer | order 928037-13-2 | 928037-13-2 distributor