E-7050 (Golvatinib)

目录号: A11396

E-7050 (Golvatinib)

E-7050 (Golvatinib) Chemical Structure

CAS NO. 928037-13-2

E7050 (also known as golvatinib is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity.

库存: 现货

规格 价格 数量
10 mg
¥ 1,100.00
25 mg
¥ 2,200.00
50 mg
¥ 3,800.00
100 mg
¥ 6,800.00
10mM * 1mL in DMSO
¥ 1,290.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

E7050 (also known as golvatinib is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity.
Targets
c-Met VEGFR2
14 nM16 nM
In vitro (25°C) DMSO 20 mg/mL (31.56 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.78 mL 78.9 mL 157.81 mL
0.5 mM 3.16 mL 15.78 mL 31.56 mL
1 mM 1.58 mL 7.89 mL 15.78 mL
5 mM 0.32 mL 1.58 mL 3.16 mL

*The above data is based on the productmolecular weight 633.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11396
MECHANISM OF ACTION N/A
M. Wt 633.69
Formula C33H37F2N7O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 928037-13-2
Synonyms N/A
SMILES CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F

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