E-7050 (Golvatinib)

Name: E-7050 (Golvatinib)
SKU: A11396
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A11396

c-Met/VEGFR-2 抑制剂

E7050（也被称为golvatinib）是一种口服生物利用度的双重激酶抑制剂，针对c-Met（肝细胞生长因子受体）和VEGFR-2（血管内皮生长因子受体-2）酪氨酸激酶，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥350.00	现货
10mg	¥595.00	现货
25mg	¥1,015.00	现货
50mg	¥1,365.00	现货
100mg	¥2,485.00	现货
*10mM 1mL in DMSO**	¥700.00	现货
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Data Sheet

SDS

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生物活性

Discription

E7050 (also known as golvatinib is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11396
分子式	C33H37F2N7O4
分子量	633.69
CAS号	928037-13-2
SMILES	CN1CCN(CC1)C2CCN(CC2)C(=O)NC3=NC=CC(=C3)OC4=CC(=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	18 mg/mL (28.4 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.78 mL	78.9 mL	157.81 mL
0.5 mM	3.16 mL	15.78 mL	31.56 mL
1 mM	1.58 mL	7.89 mL	15.78 mL
5 mM	0.32 mL	1.58 mL	3.16 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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