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(E/Z)-BCI

目录号: A22405
dual-specificity phosphatase 6 (DUSP6) 抑制剂
(E/Z)-BCI(NSC 150117)是一种具有抗炎活性的双特异性磷酸酶6(DUSP6)抑制剂。 (E/Z)-BCI 通过激活 Nrf2 信号轴并抑制 NF-κB 通路,减轻LPS诱导的炎症介质和巨噬细胞中的ROS产生。
Grouped product items
规格 价格 库存 数量
1mg
¥455.00
现货
5mg
¥1,050.00
现货
10mg
¥2,030.00
现货
25mg
¥3,290.00
现货
50mg
¥4,655.00
现货
100mg
¥6,195.00
现货
200mg
¥8,225.00
现货
10mM * 1mL in DMSO
¥1,155.00
现货
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生物活性
Discription (E/Z)-BCI (NSC 150117) is a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory activities. (E/Z)-BCI attenuates LPS-induced inflammatory mediators and ROS production in macrophage cells via activating the Nrf2 signaling axis and inhibiting the NF-κB pathway.
产品信息
目录号 A22405
分子式 C22H23NO
分子量 317.42
CAS号 15982-84-0
SMILES O=C1/C(C(NC2CCCCC2)C3=C1C=CC=C3)=C\C4=CC=CC=C4
其他名称 NSC 150117, NSC-150117, NSC150117
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2

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