(E/Z)-BCI
目录号: A22405
dual-specificity phosphatase 6 (DUSP6) 抑制剂
(E/Z)-BCI(NSC 150117)是一种具有抗炎活性的双特异性磷酸酶6(DUSP6)抑制剂。 (E/Z)-BCI 通过激活 Nrf2 信号轴并抑制 NF-κB 通路,减轻LPS诱导的炎症介质和巨噬细胞中的ROS产生。
| Discription | (E/Z)-BCI (NSC 150117) is a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory activities. (E/Z)-BCI attenuates LPS-induced inflammatory mediators and ROS production in macrophage cells via activating the Nrf2 signaling axis and inhibiting the NF-κB pathway. |
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| 目录号 | A22405 |
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| 分子式 | C22H23NO |
| 分子量 | 317.42 |
| CAS号 | 15982-84-0 |
| SMILES | O=C1/C(C(NC2CCCCC2)C3=C1C=CC=C3)=C\C4=CC=CC=C4 |
| 其他名称 | NSC 150117, NSC-150117, NSC150117 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2