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ZL0420 is a potent and selective bromodomain-containing protein 4 (BRD4) inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.75 mL | 168.74 mL | 337.47 mL |
| 0.5 mM | 6.75 mL | 33.75 mL | 67.49 mL |
| 1 mM | 3.37 mL | 16.87 mL | 33.75 mL |
| 5 mM | 0.67 mL | 3.37 mL | 6.75 mL |
*The above data is based on the productmolecular weight 296.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20136 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 296.32 |
| Formula | C16H16N4O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2230496-80-5 |
| Synonyms | ZL-0420, ZL 0420 |
| SMILES | OC1=CC(N)=C(/N=N/C2=CC(CCC(N3)=O)=C3C=C2)C=C1C.[(E)] |
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