E7820
目录号: A15456
lpha-2-integrin 抑制剂
E7820是一种小分子和芳香族磺酰胺衍生物,具有潜在的抗血管生成和抗肿瘤活性。E7820通过抑制整合素α2(integrin alpha 2),一种表达在内皮细胞上的细胞粘附分子,从而抑制血管生成。
Discription | E7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. |
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目录号 | A15456 |
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分子式 | C17H12N4O2S |
分子量 | 336.37 |
CAS号 | 289483-69-8 |
SMILES | CC1=C2C(=CNC2=C(C=C1)NS(=O)(=O)C3=CC=CC(=C3)C#N)C#N |
其他名称 | E 7820, E-7820 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 64 mg/mL (190.26 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 29.73 mL | 148.65 mL | 297.29 mL |
0.5 mM | 5.95 mL | 29.73 mL | 59.46 mL |
1 mM | 2.97 mL | 14.86 mL | 29.73 mL |
5 mM | 0.59 mL | 2.97 mL | 5.95 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2