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EBI-2511 is a highly potent and orally active EZH2 inhibitor, with an IC50 of 6 nM in Pfeffiera cell lines, respectively.
| In vitro | DMSO | 26 mg/mL (45.08 mM) | |
| Water | Insoluble | ||
| Ethanol | 11 mg/mL (19.06 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.34 mL | 86.69 mL | 173.38 mL |
| 0.5 mM | 3.47 mL | 17.34 mL | 34.68 mL |
| 1 mM | 1.73 mL | 8.67 mL | 17.34 mL |
| 5 mM | 0.35 mL | 1.73 mL | 3.47 mL |
*The above data is based on the productmolecular weight 576.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20050 |
|---|---|
| M. Wt | 576.77 |
| Formula | C34H48N4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2098546-05-3 |
| Synonyms | EBI 2511; EBI2511 |
| SMILES | CCC1=C(C(NCC2=C(C)C=C(C)NC2=O)=O)C(C=C(C3CCN(C(C)C)CC3)O4)=C4C=C1N(C5CCOCC5)CC |
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