EBI-2511
目录号: A20050
EZH2 抑制剂
EBI-2511 是一种高效且可口服的 EZH2 抑制剂,在 Pfeffiera 细胞系中的 IC50 为 6 nM。
| Discription | EBI-2511 is a highly potent and orally active EZH2 inhibitor, with an IC50 of 6 nM in Pfeffiera cell lines, respectively. | |||||
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| Cell Research |
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| 目录号 | A20050 |
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| 分子式 | C34H48N4O4 |
| 分子量 | 576.77 |
| CAS号 | 2098546-05-3 |
| SMILES | CCC1=C(C(NCC2=C(C)C=C(C)NC2=O)=O)C(C=C(C3CCN(C(C)C)CC3)O4)=C4C=C1N(C5CCOCC5)CC |
| 其他名称 | EBI 2511; EBI2511 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 26 mg/mL (45.08 mM) | |
| Water | Insoluble | ||
| Ethanol | 11 mg/mL (19.06 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.34 mL | 86.69 mL | 173.38 mL |
| 0.5 mM | 3.47 mL | 17.34 mL | 34.68 mL |
| 1 mM | 1.73 mL | 8.67 mL | 17.34 mL |
| 5 mM | 0.35 mL | 1.73 mL | 3.47 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2