Edratide
目录号: A22969
Edratide (TV 4710) 是一种基于人类抗DNA抗体互补决定区1(CDR1)的19个氨基酸合成肽,该抗体表达一种主要的特异性标志,称为16/6 Id。Edratide 降低细胞凋亡(Apoptosis)的速率,并下调 caspase-8 和 caspase-3,上调 Bcl-xL。Edratide 对于系统性红斑狼疮(SLE)的研究具有潜力。
Discription | Edratide (TV 4710) is a synthetic peptide of 19 amino acid based on the complementarity-determining region 1 (CDR1) of a human anti-DNA antibody that expresses a major idiotype denoted 16/6 Id. Edratide reduces the rates of apoptosis (Apoptosis) and down-regulates of caspase-8 and caspase-3, up-regulates Bcl-xL. Edratide has the potential for the research of systemic lupus erythematosus (SLE). |
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目录号 | A22969 |
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分子式 | C111H149N27O28 |
分子量 | 2309.53 |
CAS号 | 433922-67-9 |
Sequence | Gly-Tyr-Tyr-Trp-Ser-Trp-Ile-Arg-Gln-Pro-Pro-Gly-Lys-Gly-Glu-Glu-Trp-Ile-Gly |
Sequence shortening | GYYWSWIRQPPGKGEEWIG |
其他名称 | TV 4710 |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2