EED226
目录号: A20673
PRC2 抑制剂
EED226 是一种多梳抑制复合体2（PRC2）抑制剂，它与胚胎外胚层发育（EED）上的 K27me3-pocket 结合，并在异种移植小鼠模型中显示出强大的抗肿瘤活性。
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生物活性
| Discription | EED226 is a polycomb repressive complex 2 (PRC2) inhibitor, which binds to the K27me3-pocket on embryonic ectoderm development (EED) and shows strong antitumor activity in xenograft mice model. | |||||
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| Cell Research |
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产品信息
| 目录号 | A20673 |
|---|---|
| 分子式 | C17H15N5O3S |
| 分子量 | 369.4 |
| CAS号 | 2083627-02-3 |
| SMILES | O=S(C1=CC=C(C2=CN=C(NCC3=CC=CO3)N4C2=NN=C4)C=C1)(C)=O |
| 其他名称 | EED-226; EED 226 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Warmed: 64 mg/mL (173.25 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.07 mL | 135.35 mL | 270.71 mL |
| 0.5 mM | 5.41 mL | 27.07 mL | 54.14 mL |
| 1 mM | 2.71 mL | 13.54 mL | 27.07 mL |
| 5 mM | 0.54 mL | 2.71 mL | 5.41 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 2083627-02-3 | 2083627-02-3 供应商 | 2083627-02-3 花费 | 2083627-02-3 生产商 | 订购 2083627-02-3 | 2083627-02-3 代理商