Efalizumab is a humanized monoclonal antibody that selectively targets CD11a, the ?? subunit of lymphocyte function-associated antigen 1 (LFA-1). By modulating T cell activity, Efalizumab effectively inhibits T cell activation, adhesion to keratinocytes, and trafficking to cutaneous sites. This antibody is particularly valuable for research into the pathophysiology and potential treatments of plaque psoriasis, offering insights into T cell-mediated skin disorders.
Efalizumab is a humanized monoclonal antibody that selectively targets CD11a, the ?? subunit of lymphocyte function-associated antigen 1 (LFA-1). By modulating T cell activity, Efalizumab effectively inhibits T cell activation, adhesion to keratinocytes, and trafficking to cutaneous sites. This antibody is particularly valuable for research into the pathophysiology and potential treatments of plaque psoriasis, offering insights into T cell-mediated skin disorders.
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