EG00229
目录号: A16237
neuropilin-1/VEGF-A 抑制剂
EG00229 是首个小分子抑制剂,针对 神经节蛋白-1 (neuropilin-1) 和 血管内皮生长因子-A (VEGF-A) 的相互作用,其抑制常数(IC50)为8 uM(针对 125I-VEGF 绑定到 PAE/NRP1 细胞)。
Discription | EG00229 is the first small molecule inhibitors of the neuropilin-1 and VEGF-A interaction with an IC50 of inhibition of 8 uM(125I-VEGF binding to PAE/NRP1 cells). |
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目录号 | A16237 |
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分子式 | C19H20F3N7O7S3 |
分子量 | 611.6 |
CAS号 | 1210945-69-9 |
SMILES | C1=CC2=NSN=C2C(=C1)S(=O)(=O)NC3=C(SC=C3)C(=O)NC(CCCN=C(N)N)C(=O)O.C(=O)(C(F)(F)F)O |
其他名称 | EG 00229, EG-00229 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2