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EGFR-IN-5 is a EGFR inhibitor with IC50s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.49 mL | 87.46 mL | 174.92 mL |
| 0.5 mM | 3.5 mL | 17.49 mL | 34.98 mL |
| 1 mM | 1.75 mL | 8.75 mL | 17.49 mL |
| 5 mM | 0.35 mL | 1.75 mL | 3.5 mL |
*The above data is based on the productmolecular weight 571.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20082 |
|---|---|
| M. Wt | 571.69 |
| Formula | C31H38FN9O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2225887-26-1 |
| SMILES | OCC(CC1)CCN1C2=NC(NC3=CC=C(F)C=C3)=NC(C=N4)=C2C=C4NC5=NC=C(N6CCC(N(C)C)CC6)C=C5 |
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